immunoproliferative small intestinal disease
nounMedical Definition of immunoproliferative small intestinal disease
: a lymphoma that arises in the small intestine, is marked especially by abdominal pain, diarrhea, and malabsorption, and that chiefly affects individuals in Mediterranean regions
Note: Immunoproliferative small intestinal disease is associated with the secretion by proliferating plasma cells of truncated IgA heavy chains without the accompanying light chains.
—abbreviation IPSID— called also alpha chain disease, Mediterranean lymphoma