light chain

noun

Definition of light chain

: either of the two smaller of the four polypeptide chains comprising antibodies — compare heavy chain

Examples of light chain in a Sentence

Recent Examples on the Web

Earlier this year, a separate group of researchers at WUSTL published work showing that the levels of a protein called neurofilament light chain in the blood could predict brain damage. Katherine Ellen Foley, Quartz, "There are a lot of promising blood tests for Alzheimer’s—here’s how to keep track," 1 Aug. 2019 The mini-antibodies retain roughly the same shape but are missing the light chains. Mitch Leslie, Science | AAAS, "Mini-antibodies discovered in sharks and camels could lead to drugs for cancer and other diseases," 10 May 2018 Earlier this year, a separate group of researchers at WUSTL published work showing that the levels of a protein called neurofilament light chain in the blood could predict brain damage. Katherine Ellen Foley, Quartz, "There are a lot of promising blood tests for Alzheimer’s—here’s how to keep track," 1 Aug. 2019 Like the camel versions, the shark antibody was smaller than the regular variety and lacked light chains. Mitch Leslie, Science | AAAS, "Mini-antibodies discovered in sharks and camels could lead to drugs for cancer and other diseases," 10 May 2018 The mini-antibodies retain roughly the same shape but are missing the light chains. Mitch Leslie, Science | AAAS, "Mini-antibodies discovered in sharks and camels could lead to drugs for cancer and other diseases," 10 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'light chain.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of light chain

1964, in the meaning defined above

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More Definitions for light chain

light chain

noun

Medical Definition of light chain

: either of the two smaller of the four polypeptide chains that are subunits of antibodies

called also L chain

— compare heavy chain