von Willebrand factor
nounDefinition of von Willebrand factor
: a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease
— called also VW factor
Note: Von Willebrand factor is synthesized in endothelial cells of blood vessels and in megakaryocytes of bone marrow.
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More Definitions for von Willebrand factor
von Willebrand factor
noun
von Wil·le·brand factor
| \ vän-ˈvil-ə-ˌbränt-
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Medical Definition of von Willebrand factor
: a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease
Patients are deficient in the von Willebrand factor, one of the many blood-clotting proteins.— Paul G. Donohue, The Springfield (Massachusetts) Union-News, 6 July 1994
Note: Von Willebrand factor is synthesized in endothelial cells of blood vessels and in megakaryocytes of bone marrow.
— called also VW factor