selective estrogen receptor modulator
nounDefinition of selective estrogen receptor modulator
: any of a class of drugs (such as raloxifene or tamoxifen) that bind with estrogen receptors (as of the breast, uterus, or bone) and act as agonists to enhance estrogen activity in some tissues and as antagonists to inhibit estrogen activity in other tissues
… a selective estrogen receptor modulator, or SERM, has estrogenlike effects on bone but acts like an antiestrogen in breast and uterine tissue, thus protecting against hormone-stimulated cancers …— Jane E. Brody
— called also SERM
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