naloxone

noun
nal·​ox·​one | \ na-ˈläk-ˌsōn How to pronounce naloxone (audio) \

Definition of naloxone

: a synthetic potent antagonist of narcotic drugs (such as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence.

Examples of naloxone in a Sentence

Recent Examples on the Web

All first responders, including the Boston Fire Department and the Boston Police Department, began carrying naloxone in 2014. Alison Kuznitz, BostonGlobe.com, "Drug to treat opioid overdoses will be available in all Boston city buildings," 27 July 2019 Each of Uptown Drug’s four pharmacists is trained to administer naloxone, known by its name brand Narcan, though none has had to revive someone in the store yet. Jeannette Hinkle, azcentral, "Millions of opioid pills flooded Arizona communities during prescription drug boom," 25 July 2019 Minneapolis police carry naloxone and have administered it when applicable. Katrina Pross, Twin Cities, "At least 175 drug overdoses in MN — 17 fatal — the past 2 weeks; law enforcement stepping up efforts," 7 June 2019 In the event of an overdose, staff can administer the antidote naloxone. ... Bonnie Miller Rubin, WSJ, "Drug-Injection Sites Are Battleground in Fight Against Opioid Overdoses," 29 Apr. 2019 The company has helped fund distribution of opioid overdose antidote naloxone, for example. Jared S. Hopkins, WSJ, "At Purdue Pharma, Business Slumps as Opioid Lawsuits Mount," 30 June 2019 Now a retired firefighter is giving out free doses of an opioid antagonist naloxone, often sold under the brand name Narcan. Austen Erblat, sun-sentinel.com, "Retired firefighter trying to combat overdose epidemic with free classes and Narcan spray," 28 June 2019 Among their priorities are educating people about the dangers of fentanyl; accelerating the distribution of the opioid antidote naloxone; and guiding people toward medications for opioid use disorder. Steve Hamm, courant.com, "Fentanyl crisis prompt calls for more aggressive treatment and prevention of opioid abuse," 28 June 2019 Paramedics would offer patients the drug, often referred to by the brand name Suboxone, after their overdose had been reversed using the opioid antidote naloxone. STAT, "In national first, N.J. program will let paramedics administer buprenorphine," 26 June 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'naloxone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of naloxone

1964, in the meaning defined above

History and Etymology for naloxone

N-allyl + hydroxy- + -one

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More Definitions for naloxone

naloxone

noun
nal·​ox·​one | \ nal-ˈäk-ˌsōn How to pronounce naloxone (audio) , ˈnal-ək-ˌsōn How to pronounce naloxone (audio) \

Medical Definition of naloxone

: a potent synthetic antagonist of narcotic drugs (as morphine and fentanyl) that is administered especially in the form of its hydrochloride C19H21NO4·HCl

Note: Naloxone is administered by injection or as a nasal spray to reverse the effects of opioids and especially in the emergency treatment of opioid overdose. It is also administered in combination with buprenorphine in the form of a dissolvable tablet placed under the tongue or a film placed inside the cheek to treat opioid dependence. Trademarks for preparations containing naloxone include Bunavail, Evzio, Narcan, Suboxone, and Zubsolv.