karyorrhexis

noun
kar·​y·​or·​rhex·​is | \ ˌkar-ē-ȯr-ˈek-səs How to pronounce karyorrhexis (audio) \
plural karyorrhexes\ -​ˌsēz How to pronounce karyorrhexes (audio) \

Medical Definition of karyorrhexis

: a degenerative cellular process involving fragmentation of the nucleus and the breakup of the chromatin into unstructured granules — compare karyolysis