hypermutation
noun
hy·per·mu·ta·tion
| \ -myü-ˈtā-shən
\
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Medical Definition of hypermutation
: the process of producing an unusually high number of mutations or changes
During maturation, B cells use somatic hypermutation to increase their diversity.— Thomas A.Waldmann, Science, 21 June 1991
also
: a mutation or change produced by hypermutation