bortezomib
noun
bor·tez·o·mib
| \ ˌbȯr-ˈte-zō-ˌmib
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Medical Definition of bortezomib
: an antineoplastic drug C19H25BN4O4 administered by intravenous or subcutaneous injection especially in the treatment of multiple myeloma
Note: Bortezomib inhibits the activity of proteolytic proteasomes, which results in an increased concentration of proteins in a cell. This buildup of proteins is thought to induce apoptosis in some types of cancer cells. Bortezomib is marketed under the trademark Velcade.
Bortezomib induces apoptosis in a wide variety of cancer-cell lines and other transformed cells, yet it has relatively few toxic effects on normal cells.— Beverly S. Mitchell, The New England Journal of Medicine, 26 June 2003