Lesch-Nyhan syndrome
noun
Lesch-Ny·han syndrome
| \ ˈlesh-ˈnī-ən-
\
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Medical Definition of Lesch-Nyhan syndrome
: a rare and usually fatal genetic disorder of male children that is inherited as an X-linked recessive trait and is characterized by hyperuricemia, intellectual disability, spasticity, compulsive biting of the lips and fingers, and a deficiency of hypoxanthine-guanine phosphoribosyltransferase
— called also Lesch-Nyhan disease