COX-2

noun
\ ˈkäks-ˈtü How to pronounce COX-2 (audio) \

Medical Definition of COX-2

1 : the isoform of cyclooxygenase that is expressed especially in the brain and kidneys and at sites of inflammation … the enzyme (called COX-2) that triggers the joint inflammation causing arthritis pain.— Andrew Weil, Self Healing, July 2006