Angelman syndrome
noun
An·gel·man syndrome
| \ ˈan-jəl-mən-, ˈān-
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variants:
also Angelman's syndrome \ -mənz-
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Medical Definition of Angelman syndrome
: a genetic disorder characterized by severe intellectual disability, seizures, ataxic gait, jerky movements, lack of speech, microcephaly, and frequent smiling and laughter