Alport syndrome
noun
Al·port syndrome
| \ ˈal-ˌpȯrt-
\
\
variants:
or Alport's syndrome
Medical Definition of Alport syndrome
: a genetic disorder of the kidneys that is usually inherited as an X-linked trait, is typically more severe in males, and is characterized especially by blood in the urine, hearing loss, abnormalities of the eye, and progressive renal failure
Note: Alport syndrome is caused by mutations in genes encoding a type of collagen normally present in basement membranes.
Most victims of Alport syndrome experience progressive kidney failure, often requiring a kidney transplant or prolonged kidney dialysis.— William Booth, The Washington Post, 8 June 1990