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statin

noun
stat·​in | \ ˈsta-tᵊn How to pronounce statin (audio) \

Definition of statin

: any of a group of drugs (such as lovastatin and simvastatin) that inhibit the synthesis of cholesterol and promote the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma

Examples of statin in a Sentence

Recent Examples on the Web

Of a thousand people who take statins for five years, the drugs will help only eighteen to avoid a major heart attack or stroke. Hannah Fry, The New Yorker, "What Statistics Can and Can’t Tell Us About Ourselves," 2 Sep. 2019 Say a patient is prescribed a statin, a type of drug to lower cholesterol which has proved useful in reducing heart disease. The Economist, "Why America’s biggest charities are owned by pharmaceutical companies," 15 Aug. 2019 Medical advances such as coronary-artery-bypass surgery, defibrillators, better blood-pressure drugs and statins also saved lives. Betsy Mckay, WSJ, "Heart Attack at 49—America’s Biggest Killer Makes a Deadly Comeback," 21 June 2019 Pfizer agreed Monday to combine its off-patent drugs division, which controls treatments like the statin Lipitor, with the pharmaceutical company Mylan, creating a potential powerhouse in the business of medicines without patent protections. Michael J. De La Merced, BostonGlobe.com, "Pfizer is to merge off-patent drug unit with Mylan," 29 July 2019 For example, statins to treat high cholesterol were giant commercial successes in the previous two decades, but now are available as cheap generic drugs. Charley Grant, WSJ, "A Big, Fatty Opportunity for Big Pharma," 18 Jan. 2019 The patients in the trial were on statins and had a wide range of triglyceride levels. Betsy Mckay, WSJ, "New Guidelines for Treating High Cholesterol Take a Personal Approach," 10 Nov. 2018 Because these drugs often cause high cholesterol, for example, someone taking antipsychotics may also take a statin (drugs prescribed to help lower cholesterol). Kasandra Brabaw, SELF, "7 Myths You Might Believe About Antipsychotic Medications," 7 Dec. 2018 Fungi are hailed for their medical uses, having proved vital for antibiotics and for cholesterol-lowering statins, but even fungus fans admit there is a macabre element to some aspects of fungi life. Gregory Katz, The Seattle Times, "Royal Botanic Garden seeks respect for world’s fungus," 11 Sep. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'statin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of statin

1985, in the meaning defined above

History and Etymology for statin

from -statin (as in lovastatin)

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More Definitions for statin

statin

noun
stat·​in | \ ˈstat-ᵊn How to pronounce statin (audio) \

Medical Definition of statin

: any of a group of lipid-lowering drugs (as lovastatin and simvastatin) that function by inhibiting a liver enzyme which controls the synthesis of cholesterol and by promoting the production of LDL-binding receptors in the liver resulting in a usually marked decrease in the level of LDL and a modest increase in the level of HDL circulating in blood plasma