: a protease in the juice of unripe papaya that is used especially as a tenderizer for meat and in medicine (as in the topical debridement of necrotic tissue)
: a crystallizable protease in the juice of the green fruit of the papaya obtained usually as a brownish powder and used chiefly as a tenderizer for meat and in medicine as a digestant and as a topical agent in the debridement of necrotic tissue