monoclonal
adjective
mono·clo·nal
| \ ˌmä-nə-ˈklō-nᵊl
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Definition of monoclonal
: produced by, being, or composed of cells derived from a single cell
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Examples of monoclonal in a Sentence
Recent Examples on the Web
There’s a monoclonal antibody used in the A4 study (https://a4study.org). — San Diego Union-Tribune, "Progress in understanding Alzheimer’s disease genetics, hope remains for drugs in testing," 2 Sep. 2019 One of the drugs, REGN-EB3, is a cocktail of three monoclonal antibodies against Ebola made by Regeneron Pharmaceuticals of Tarrytown, New York. — Amy Maxmen, Scientific American, "Two Ebola Drugs Show Promise Amid Ongoing Outbreak," 13 Aug. 2019 The study will now focus on Regeneron's REGN-EB3 and a monoclonal antibody called mAb114. — NBC News, "Two experimental Ebola treatments being tested in Congo show promise," 12 Aug. 2019 By contrast, 33 percent of those who received remdesivir, an antiviral drug, and 24 percent of those who got ZMapp, an older cocktail of monoclonal antibodies, died. — Donald G. Mcneil Jr., BostonGlobe.com, "Two new Ebola treatments prove highly effective in Congo epidemic, will be offered to all patients," 12 Aug. 2019 Later, the pharmacopoeia expanded to include large and complex proteins—from insulin to monoclonal antibodies. — Siddhartha Mukherjee, The New Yorker, "The Promise and Price of Cellular Therapies," 15 July 2019 Drugs derived from recombinant DNA and those made with another biotech method—monoclonal antibody technology—dominated drug development. — Henry I. Miller, WSJ, "Follow the FDA’s Self-Interest," 28 Oct. 2018 The monoclonal antibody daratumumab, sold by the Janssen unit of Johnson & Johnson under the brand name Darzalex, was first approved in 2015 for people with late-stage disease. — Karen Weintraub, STAT, "Once quickly lethal and still humbling, multiple myeloma may be in a ‘golden age’ of treatment," 29 May 2018 Still, monoclonal antibody treatment will not be for everyone. — R. Allan Purdy, Scientific American, "Can Anything Stop My Migraine?," 1 May 2017These example sentences are selected automatically from various online news sources to reflect current usage of the word 'monoclonal.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
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More Definitions for monoclonal
monoclonal
adjective
mono·clo·nal
| \ ˌmän-ə-ˈklōn-ᵊl
\
\
Medical Definition of monoclonal
(Entry 1 of 2)
: produced by, being, or composed of cells derived from a single cell
a monoclonal tumor
especially
: relating to or being an antibody derived from a single cell in large quantities for use against a specific antigen (as a cancer cell)
monoclonal
nounMedical Definition of monoclonal (Entry 2 of 2)
: a monoclonal antibody