1 isotretinoin | Definition of isotretinoin

isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtre-tə-ˌnȯin How to pronounce isotretinoin (audio) \

Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, inhibits sebaceous gland function and keratinization, and is used in the treatment of severe inflammatory acne

Examples of isotretinoin in a Sentence

Recent Examples on the Web

For example, retinoids such as tretinoin and isotretinoin are a no-no during pregnancy because they have been linked to birth defects. Nikhita Mahtani, SELF, "How to Safely Treat Your Postpartum Acne," 24 Apr. 2019 But mental health effects from isotretinoin are now being cited in the trial of a 15-year-old charged with first-degree murder and 10 other counts in the alleged stabbing of a 20-year-old woman in Colorado last year. Macaela Mackenzie, Allure, "Isotretinoin, the Drug Formerly Known as Accutane, May Be Cited in Upcoming Murder Trial," 2 Mar. 2018 This isn't the first time the finger has been pointed at the link between isotretinoin and mental health in a court case. Zoë Weiner, Teen Vogue, "Acne Drug Commonly Known as Accutane May Be Cited in a Murder Case," 2 Mar. 2018 Quite a bit more troublesome is that isotretinoin is linked to birth defects. Sarah Klein, Health.com, "The Truth About Scary Accutane Side Effects," 28 Feb. 2018 Teen Vogue has reached out to the teen's legal team and Hoffman-La Roche, manufacturers of isotretinoin, for comment and will update this story as more information becomes available. Zoë Weiner, Teen Vogue, "Acne Drug Commonly Known as Accutane May Be Cited in a Murder Case," 2 Mar. 2018 Those familiar with isotretinoin, the drug formerly known under the brand name Accutane — a heavy-duty prescription acne medication — are probably also familiar with the drug's potential side effects, which include some serious warnings. Macaela Mackenzie, Allure, "Isotretinoin, the Drug Formerly Known as Accutane, May Be Cited in Upcoming Murder Trial," 2 Mar. 2018 The most common side effects of isotretinoin are not the type of attention-grabbing symptoms making headlines. Sarah Klein, Health.com, "The Truth About Scary Accutane Side Effects," 28 Feb. 2018 Studies of the drug performed over the last decade have suggested links between isotretinoin and anxiety, depression, bipolar disorder, and even psychosis. Macaela Mackenzie, Allure, "Isotretinoin, the Drug Formerly Known as Accutane, May Be Cited in Upcoming Murder Trial," 2 Mar. 2018

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First Known Use of isotretinoin

1979, in the meaning defined above

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More Definitions for isotretinoin

isotretinoin

noun
iso·​tret·​i·​noin | \ ˌī-sō-ˈtret-ə-ˌnȯin How to pronounce isotretinoin (audio) \

Medical Definition of isotretinoin

: a cis isomer of retinoic acid that is a synthetic derivative of vitamin A, that inhibits sebaceous gland function and keratinization, and that is administered in the treatment of severe inflammatory acne but is contraindicated in pregnancy because of its implication as a cause of birth defects

called also 13-cis-retinoic acid, retinoic acid

— see accutane