downstream

adverb or adjective
down·​stream | \ ˈdau̇n-ˈstrēm How to pronounce downstream (audio) \

Definition of downstream

1 : in the direction of or nearer to the mouth of a stream floating downstream located two miles downstream
2 : in or toward the latter stages of a usually industrial process or the stages (such as marketing) after manufacture improving profits downstream downstream products
3 biochemistry : toward the end of a series of cellular processes : following a linked molecular event occurring in a sequence But by looking downstream of the tumor suppressors [genes] at the proteins they influence, drug developers hope to find good targets.— Marcia Barinaga

Examples of downstream in a Sentence

Recent Examples on the Web

Does Apple expect developers to support mobile first and foremost, with other platforms coming downstream from that? Samuel Axon, Ars Technica, "Catalyst deep dive: The future of Mac software according to Apple and devs," 1 July 2019 The second victim was rescued further downstream by a MillerCoors employee, firefighters said. Kieran Nicholson, The Denver Post, "MillerCoors employee, emergency personnel rescue two tubers toppled in Clear Creek," 28 June 2019 The picture of the two of them, taken by a news photographer after their bodies were discovered downstream the following day, has been held up as a symbol of the great lengths to which migrants will go to live in America. Dahleen Glanton, chicagotribune.com, "Column: The drowning of father and daughter crossing the Rio Grande shows migrants’ desperation for asylum, and U.S. determination not to grant it.," 26 June 2019 Once the ceremonies were completed, the barks returned downstream to Karnak. National Geographic, "Egypt’s pharaohs welcomed summer with this fabulous festival," 25 June 2019 While two brown bear teenagers kept their distance further downstream, there were a few disconcerting moments when two black bears suddenly appeared on our side of the creek right at the edges of our deck. Plain Dealer Guest Writer, cleveland.com, "Cruising Alaska's Inside Passage, shore excursions feature close encounters with bears, icebergs (photos)," 17 Jan. 2018 But properties downstream from the 91-year-old dam likely wouldn’t see a huge impact, officials have said. Joshua Fechter, ExpressNews.com, "Proposal to drain Lake McQueeney in wake of dam failures ripples through small town," 11 Aug. 2019 The victim, a 16-year-old girl on vacation from Kansas, was found shortly after 9 a.m. on Thursday approximately 100 yards downstream from the Devil’s Punchbowl, the news release said. Carina Julig, The Denver Post, "Body of teen girl swept away in Roaring Fork River found," 1 Aug. 2019 The man was arrested, but police say this is becoming a bigger issue for the city because drugs in the sewer system end up in retention ponds for processing before they are sent downstream. Doug Criss, CNN, "Tennessee police department says it was joking about people creating 'meth gators' by flushing drugs down toilet," 22 July 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'downstream.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of downstream

1591, in the meaning defined at sense 1

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More Definitions for downstream

downstream

adverb or adjective

Financial Definition of downstream

What It Is

Downstream refers to the benefits (or costs) that will ultimately result from decisions made today.

How It Works

In finance, a series of investments might be made with the anticipation that at a point in time in the future these efforts will yield a series of returns.  These returns occur after the initial investments.  As a result, they are referred to as downstream benefits.  Similarly, investments can have downstream "costs" as well.   The expectation is that the downstream benefits will outweigh the downstream costs.

At the same time, because the future is hard to predict, downstream effects are often unanticipated, setting off unintended costs and consequences.

Why It Matters

It is important to consider the "downstream" effects of an investment decision since it will impact ones future economic performance.

Source: Investing Answers

downstream

adverb

English Language Learners Definition of downstream

: in the direction in which a stream, river, etc., flows

downstream

adverb
down·​stream | \ ˈdau̇n-ˈstrēm How to pronounce downstream (audio) \

Kids Definition of downstream

: in the direction a stream is flowing paddling downstream

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downstream

adverb or adjective
down·​stream | \ ˌdau̇n-ˈstrēm How to pronounce downstream (audio) \

Medical Definition of downstream

1 : in the same direction along a molecule of DNA or RNA as that in which transcription and translation take place and toward the end having a hydroxyl group attached to the position labeled 3′ in the terminal nucleotide a nucleotide sequence located downstream from the regulatory gene effects on the expression of downstream genes — compare upstream sense 1
2 : toward the end of a series of cellular processes : following a linked molecular event occurring in a sequence But by looking downstream of the tumor suppressors [genes] at the proteins they influence, drug developers hope to find good targets.— Marcia Barinaga, Science, 7 Nov. 1997 The tyrosine kinase activity of phosphorylated EGFR [epidermal growth factor receptor] in cancer cells results in the phosphorylation of downstream proteins that incite cell proliferation, invasion, metastasis, and inhibition of apoptosis.— Jonathan E. Dowell and John D. Minna, The New England Journal of Medicine, 24 Feb. 2005