clozapine

noun
clo·​za·​pine | \ ˈklō-zə-ˌpēn How to pronounce clozapine (audio) \

Definition of clozapine

: an antipsychotic drug C18H19ClN4 used in the treatment of schizophrenia

Examples of clozapine in a Sentence

Recent Examples on the Web

Research suggests that chlorpromazine is the most likely to cause seizures among typical antipsychotics while clozapine is most likely among atypicals. Kimberly Truong, SELF, "11 Side Effects of Antipsychotics You Should Know About," 7 Dec. 2018 Twenty days later, Mathew stopped regularly taking clozapine, an antipsychotic used to treat schizophrenia. oregonlive.com, "Kicked to the curb: How the state failed fragile mentally ill Oregonians," 22 June 2019 Research suggests that this is more likely to be an issue with typical antipsychotics than atypical ones, such as olanzapine, clozapine, and aripiprazole—with the exception of risperidone. Kimberly Truong, SELF, "11 Side Effects of Antipsychotics You Should Know About," 7 Dec. 2018 Research suggests that chlorpromazine is the most likely to cause seizures among typical antipsychotics while clozapine is most likely among atypicals. Kimberly Truong, SELF, "11 Side Effects of Antipsychotics You Should Know About," 7 Dec. 2018 The report thoughtfully takes a strong stance and recommends the wider use of clozapine, an atypical antipsychotic medication that, for people with schizophrenia, is often superior to other medications. D. J. Jaffe, National Review, "The Way Forward on Federal Mental Health Policy," 18 Dec. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'clozapine.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of clozapine

1970, in the meaning defined above

History and Etymology for clozapine

International Scientific Vocabulary chlor- + -zapine, alteration of -azepine (as in benzodiazepine)

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More Definitions for clozapine

clozapine

noun
clo·​za·​pine | \ ˈklō-zə-ˌpēn How to pronounce clozapine (audio) \

Medical Definition of clozapine

: an antipsychotic drug C18H19ClN4 with serious side effects (as seizures and agranulocytosis) that is used in the management of schizophrenia

Note: Clozapine is marketed under the trademark Clozaril.