antimetabolite
noun
an·ti·me·tab·o·lite
| \ ˌan-tē-mə-ˈta-bə-ˌlīt
, ˌan-ˌtī-\
, ˌan-ˌtī-\
Definition of antimetabolite
: a substance that is structurally similar to a metabolite (such as a coenzyme) and that serves to inhibit a particular cellular function (such as DNA synthesis) by interfering with or blocking the metaboliteʼs action
From the start [Gertrude] Elion concentrated her research on using purine and pyrimidine antimetabolites to interfere with the synthesis of nucleic acids …— Mairin Brennan
Other Words from antimetabolite
antimetabolic
\ ˌan-tē-ˌme-tə-ˈbä-lik
, ˌan-tī- \
adjective
, ˌan-tī- \
adjective
a drug with antimetabolic action
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More Definitions for antimetabolite
antimetabolite
noun
an·ti·me·tab·o·lite
| \ ˌant-i-mə-ˈtab-ə-ˌlīt, ˌan-ˌtī-
\
\
Medical Definition of antimetabolite
: a substance that is structurally similar to a metabolite (as a coenzyme) and that serves to inhibit a particular cellular function (as DNA synthesis) by interfering with or blocking the metaboliteʼs action
Antimetabolites, such as methotrexate masquerade as essential nutrients, which the cell uses instead of real nutrients and thus dies.— Jane E. Brody antimetabolite therapy
Other Words from antimetabolite
antimetabolic
\ -ˌmet-ə-ˈbäl-ik
\
adjective
\
adjective
In addition to its antimetabolic effects, methotrexate has immunological effects …
— Robert S. Stern