1 antigen | Definition of antigen

antigen

noun
an·​ti·​gen | \ ˈan-ti-jÉ™n How to pronounce antigen (audio) , -ËŒjen\

Definition of antigen

: any substance (such as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (such as a protein) and that is capable of binding with a product (such as an antibody or T cell) of the immune response

Keep scrolling for more

Other Words from antigen

antigenic \ ËŒan-​ti-​ˈje-​nik How to pronounce antigenic (audio) \ adjective
antigenically \ -​ni-​k(É™-​)lÄ“ How to pronounce antigenically (audio) \ adverb
antigenicity \ -​jÉ™-​ˈni-​sÉ™-​tÄ“ How to pronounce antigenicity (audio) \ noun

Did You Know?

An antibody is a protein produced by your immune system to fight outside invaders. Since the enemy substance actually triggers the production of antibodies, such substances are called antigens—anti- being short for antibody, and -gen meaning "producer". (In a similar way, an allergen produces an allergy, and a pathogen produces a pathology or disease.) Antigens are often rodlike structures that stick out from the surface of an invading organism—usually a bacterium or a virus—and allow it to attach itself to cells in the invaded body. But unfortunately for them, in doing so they let the immune system know they're present, and the body is flooded with an army of Pac-Man-like antibodies.

Examples of antigen in a Sentence

Recent Examples on the Web

First things first: All vaccines only contain very small amounts of antigens. Carolyn L. Todd, SELF, "What Parents Need to Know About the Immunization Schedule for Kids," 26 Aug. 2019 To do that, researchers have needed to identify antigens unique to such cancers, and create CAR’s that can recognize them. Charles Graeber, WIRED, "How Scientists Built a ‘Living Drug’ to Beat Cancer," 25 July 2019 The vaccines were created with little bits of the bacteria -- called antigens -- instead of entire cells. Arman Azad, CNN, "Whooping cough vaccine becomes less effective over time, study says," 10 June 2019 Other immune cells produce antibodies that can also grab onto the antigens and help kill the pathogen. Quanta Magazine, "Breakthrough DNA Editor Born of Bacteria," 6 Feb. 2015 The first method used, which compared antigens on the white blood cells of parents and children, could establish paternity with an accuracy rate of eighty per cent. Margaret Talbot, The New Yorker, "The Paternity Reveal," 24 June 2019 One technique currently being studied involves increasing the number of antigens -- the bits of B. pertussis cells that are recognized by the immune system -- to better mimic the older whole-cell vaccines. Arman Azad, CNN, "Whooping cough vaccine becomes less effective over time, study says," 10 June 2019 One of them, called CAR-T (for chimeric antigen receptor T-cell therapy), removes a patient’s own immune cells and genetically re-engineers them to bind to a specific protein on the surface of the patient’s cancer cells. Ezekiel Emanuel, WSJ, "We Can’t Afford the Drugs That Could Cure Cancer," 20 Sep. 2018 Drug companies have spent big on chimeric antigen receptor T-cells, or CAR-T, cancer therapies. Charley Grant, WSJ, "Big Pharma’s Big Cancer Hope Is Fizzling," 8 Feb. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'antigen.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of antigen

1908, in the meaning defined above

History and Etymology for antigen

German, from French antigène, from anticorps antibody + -gène -gen

Keep scrolling for more

Keep scrolling for more

More Definitions for antigen

antigen

noun

English Language Learners Definition of antigen

medical : a harmful substance that causes the body to produce antibodies

antigen

noun
an·​ti·​gen | \ ˈant-i-jÉ™n How to pronounce antigen (audio) \

Medical Definition of antigen

: any substance (as an immunogen or a hapten) foreign to the body that evokes an immune response either alone or after forming a complex with a larger molecule (as a protein) and that is capable of binding with a product (as an antibody or T cell) of the immune response

Other Words from antigen

antigenic \ ËŒant-​i-​ˈjen-​ik How to pronounce antigenic (audio) \ adjective
antigenically \ -​i-​k(É™-​)lÄ“ How to pronounce antigenically (audio) \ adverb

Keep scrolling for more

More from Merriam-Webster on antigen

Spanish Central: Translation of antigen

Nglish: Translation of antigen for Spanish Speakers

Britannica English: Translation of antigen for Arabic Speakers

Britannica.com: Encyclopedia article about antigen